[99mTc]-Technetium has become the most widely used radionuclide in diagnostic nuclear medicine due to its physical characteristics of short half-life, low energy of its mono-energetic gamma rays and ease of its incorporation into a wide range of radiopharmaceuticals.
[99mTc]-Technetium is formed from the decay of a parent radionuclide, molybdenum-99, which through this parent-daughter process, can be provided in a convenient, readily available form such as the recently introduced COLTECH Technetium Generator.
There are other Column Generator products such as geltech generator and TCM 2 solvent extraction generator which can also be used for preparation of [99mTc]-Technetium labelled radiopharmaceuticals with Technetium Cold Kits supplied by BRIT.
Some of the technetium labelled compounds and their clinical uses are listed:
|Radiopharmaceutical||BRIT Kit Code||Short form||Clinical Use|
|99mTc-Phytate||TCK-16||99m Tc-Phy||Liver imaging|
|99mTc Sulphur Colloid||TCK-5||99mTcS/C||Liver and spleen imaging|
|99mTc Mebrofenin||TCK-39||99m Tc-mebro||Hepatobilliary function|
|99mTc Methylene di Phosphonate||TCK-30||99mTc-MDP||Bone Scan|
|99mTc Red Blood Cells||TCK-38||99mTc-RBC||Cardiac Function and Blood Pool Scans|
|99mTc Mibi||TCK-50||99mTc-MIBI||Myocardial Perfusion (Heart Muscle Blood Flow)|
|99mTc Diethylene Triamine Penta Acetic Acid||TCK-7||99mTc-DTPA||Renal Function|
|99mTc Ethylene di cysteine||TCK-43||99mTc-EC||Renal tubular function|
|99mTc Glucoheptonate||TCK-15||99m Tc-GHA||Kidney imaging|
|99mTc Ethyl cystienate dimer||TCK-42||99mTc- ECD||Brain Scan and Scans for Infection|